RISK FACTORS ASSOCIATED WITH PULMONARY TB INCIDENCE IN CHILDREN IN BANDA ACEH
Abstract
Background: Pulmonary TB in children is still a serious public health problem in Aceh Province, this can be seen from the increase in cases in the last three years that are suspected to be related to immunization status, nutritional status, income, knowledge, the presence of TB sufferers, occupancy density and exposure to cigarette smoke. This study aims to determine the risk factors associated with pulmonary TB incidence in children in Banda Aceh. Method: This research is an analytic observational study using a case control design. The population in this study was children suffering from pulmonary TB in Banda Aceh as many as 30 respondents. Using a ratio of 1:2 comparison, the research sample of 90 respondents consisted of 30 cases and 60 controls. Data collection was conducted from 15 October to 15 December, conducted in the respondent's home. Data analysis using conditional multiple logistic regression test. Results: Risk factors associated with pulmonary TB in childrenare: the employment of self-employed fathers (p=0.046; OR=2.7; 95% CI: 1.01-7.50), low income (p=0.046; OR=2.7; 95% CI: 1.01-7.50), the presence of TB patients in home (p=0.001; OR=31; 95% CI: 4.11-234), cigarette smoke exposure (p=0.004; OR=4; 95% CI: 1.54-10.3), no BCG immunization (p=0.023; OR=4.6; 95% CI: 1.23-17.2), malnutrition status with the occurrence of pulmonary TB in children in Banda Aceh (p=0.002; OR=5.9; 95% CI: 1.93-18.5). The results of the multivariate analysis concluded that the tendency of pulmonary TB in children in the city of Banda Aceh to occur in the presence of TB patients at home was almost 4 times more dominant than other variables. Recommendation: To Banda Aceh Health Office in order to increase the number of pulmonary TB screening in children, especially in children with parents who suffer from pulmonary TB.
Keywords
Full Text:
PDFReferences
Aceh, DKB., Laporan Triwulan Penemuan dan Pengobatan Pasien TB, Banda Aceh: Dinkes Kota Banda Aceh; 2018.
Brosch, R., Gordon, S. V., Garnier, T., Eiglmeier, K., Frigui, W., Valenti, P., et al., Genome Plasticity of BCG and Impact on Vaccine Efficacy, Proceedings of the National Academy of Sciences; 2007, Vol. 104, No. 13, pp. 5596-601.
den Boon, S., Verver, S., Marais, B. J., Enarson, D. A., Lombard, C. J., Bateman, E. D., et al., Association Between Passive Smoking and Infection with Mycobacterium Tuberculosis in Children, Pediatric; 2007, Vol. 119, No. 4, pp. 734-9.
Diani, A., Setyanto, D. B., Nurhamza W., Proporsi Infeksi Tuberkulosis dan Gambaran Faktor Risiko pada Balita yang Tinggal dalam Satu Rumah dengan Pasien Tuberkulosis Paru Dewasa, Sari Pediatri; 2016, Vol. 13, No. 1, pp. 62-9.
Dinkes Aceh, Jumlah Kasus Tuberkulsis Anak Tahun 2019, Banda Aceh: Dinkes Provisni Aceh; 2019.
Dodd, P. J., Gardiner, E., Coghlan, R., Seddon, J. A., Burden of Childhood Tuberculosis in 22 High-Burden Countries: a Mathematical Modelling Study, The Lancet Global Health; 2014, Vol. 2, No. 8.
Drobac, P. C., Shin, S. S., Huamani, P., Atwood, S., Furin, J., Franke, M. F., et al., Risk Factors for in-Hospital Mortality Among Children with Tuberculosis: the 25-Year Experience in Peru, Pediatrics; 2012:
Febrian, M. A., Faktor-faktor yang Berhubungan dengan Kejadian TB Paru Anak di Wilayah Puskesmas Garuda Kota Bandung, Jurnal Keperawatan BSI; 2015, Vol. 3, No. 2.
Glader, P., Mller, S., Lilja, J., Wieslander, E., Lfdahl, C-G., von Wachenfeldt, K., Cigarette Smoke Extract Modulates Respiratory Defence Mechanisms Through Effects on T-Cells and Airway Epithelial Cells, Respiratory Medicine; 2006, Vol. 100, No. 5.
Indreswari, S. A., Suharyo, S., Diagnosis Dini Tuberkulosis pada Kontak Serumah dengan Penderita Tuberkulosis Paru melalui Deteksi Kadar IFN-?, National Public Health Journal; 2014, Vol. 9, No. 1, pp. 32-8.
Jahiroh, N., Prihartono, N., Hubungan Stunting dengan Kejadian Tuberkulosis pada Balita, The Indonesian Journal of Infectious Diseases; 2017, Vol. 1, No. 2, pp. 6-13.
Jubulis, J., Kinikar, A., Ithape, M., Khandave, M., Dixit, S., Hotalkar, S., et al., Modifiable Risk Factors Associated with Tuberculosis Disease in Children in Pune, India, The International Journal of Tuberculosis and Lung Disease; 2014, Vol. 18, No. 2, pp. 198-204.
Kartasasmita, C. B., Epidemiologi Tuberkulosis, Sari Pediatri; 2016, Vol. 11, No. 2, pp. 124-9.
Kemenkes, R., Tuberkulosis, Jakarta: Pusat Data dan Informasi Kemenkes RI; 2018.
Kholifah, S. N., Indreswari S. A., Faktor Terjadinya Tuberkulosis Paru pada Anak Berdasarkan Riwayat Kontak Serumah, VISIKES, Jurnal Kesehatan Masyarakat; 2015, Vol. 14, No. 2.
Leung, C. C., Lam, T. H., Ho, K. S., Yew, W. W., Tam, C. M., Chan, W. M., et al., Passive Smoking and Tuberculosis, Archives of Internal Medicine; 2010, Vol. 170, No. 3, pp. 287-92.
Lienhardt, C., Fielding, K., Sillah, J., Tunkara, A., Donkor, S., Manneh, K., et al., Risk Factors for Tuberculosis Infection in Sub-Saharan Africa: a Contact Study in the Gambia, American Journal of Respiratory and Critical Care Medicine; 2003, Vol. 168, No. 4, pp. 448-55.
Lin, H-H., Ezzati, M., Murray, M., Tobacco Smoke, Indoor Air Pollution and Tuberculosis: a Systematic Review and Meta-Analysis, PLoS Medicine; 2007, Vol. 4, No. 1.
Lutfi, A., Tuberkulosis Nosokomial, Jurnal Tuberkulosis; 2012, Vol. 8, pp. 30-31.
Marais, B. J., Schaaf, H. S., Tuberculosis in Children, Cold Spring Harbor Perspectives in Medicine; 2014, Vol. 4, No. 9.
Michelsen, S., Soborg, B., Koch, A., Carstensen, L., Hoff, S., Agger, E., et al., The Effectiveness of BCG Vaccination in Preventing Mycobacterium Tuberculosis Infection and Disease in Greenland, Thorax; 2014, Vol. 69, No. 9, pp. 851-6.
Nurwitasari, A., Wahyuni, C. U., Pengaruh Status Gizi dan Riwayat Kontak Terhadap Kejadian Tuberkulosis Anak di Kabupaten Jember, Jurnal Berkala Epidemiologi; 2015, Vol. 3, No. 2, pp. 158-69.
Rachim, R. D. A., Hubungan Pemberian Imunisasi BCG dengan Kejadian Tuberkulosis pada Anak di Puskesmas Pandian Kabupaten Sumenep, Jurnal Ilmu Kesehatan dan Kedokteran Keluarga; 2017, Vol. 10, No. 2, pp. 109-14.
Roy, A., Eisenhut, M., Harris, R., Rodrigues, L., Sridhar. S., Habermann, S., et al., Effect of BCG Vaccination Against Mycobacterium Tuberculosis Infection in Children: Systematic Review and Meta-Analysis, BMI; 2014, 349:g4643.
Roy, A., Eisenhut, M., Harris, R., Rodrigues, L., Sridhar, S., Habermann, S., et al., The Protective Effect of BCG Vaccination Against Mycobacterium Tuberculosis Infection in Children: a Systematic Review, European Respiratory Journal; 2014, Vol. 44 (Suppl 58).
RSUDZA, Laporan Kunjungan Pengobatan TB Paru, Banda Aceh: RSUDZA; 2020.
Rusnoto, R., Faktor-faktor yang Berhubungan dengan Kejadian TB Paru pada Usia Dewasa (Studi Kasus di Balai Pencegahan dan Pengobatan Penyakit Paru Pati), Jurnal Epidemiologi; 2008.
Rukmini, R., Chatarina, U., Faktor-faktor yang Berpengaruh terhadap Kejadian TB Paru Dewasa di Indonesia (Analisis Data Riset Kesehatan Dasar Tahun 2010), Buletin Penelitian Sistem Kesehatan; 2011, Vol. 14, No. 4.
Saiman, L., San Gabriel P., Schulte, J., Vargas, M. P., Kenyon, T., Onorato, I., Risk Factors for Latent Tuberculosis Infection Among Children in New York City, Pediatrics; 2001, Vol. 107, No. 5, pp. 999-1003.
Schwenk, A., Macallan, D. C., Tuberculosis, Malnutrition and Wasting, Current Opinion in Clinical Nutrition & Metabolic Care; 2000, Vol. 3, No. 4, pp. 285-91.
Singh, M., Mynak, M., Kumar, L., Mathew, J., Jindal, S., Prevalence and Risk Factors for Transmission of Infection Among Children in Household Contact with Adults Having Pulmonary Tuberculosis, Archives of Disease in Childhood; 2005, Vol. 90, No. 6, pp. 624-8.
DOI: https://doi.org/10.37598/jukema.v7i1.1066
Refbacks
- There are currently no refbacks.